The Complete Formulation:
Skinception™ Rosacea Relief Serum has been scientifically formulated with a series of ingredients that work synergistically to reduce the symptoms associated with rosacea outbreaks including facial redness, inflammation, and prickling heat.
The complete formulation includes:
The trade name for teprenone, a new breakthrough in skincare, anti-aging, and rosacea treatment that works on skin cells at the DNA level. Renovage™ protects the threads of DNA from unraveling so that a cell can continue to divide without harm to DNA, which triggers the death of the cell. In so doing, Renovage™ has been clinically proven to prolong the life of cells by one-third.
Renovage™ is reported to improve skin function (i.e., hydration, barrier function, and pigmentation) as well as skin structure (i.e., firmness, elasticity, wrinkles, fine lines, pore size, and erythrosis).
In a clinical study conducted with a group of 25 women, all of whom were age 45 or older, Renovage™ was applied twice daily for six months. The women’s skin was evaluated at one month, three months, and six months. A number of anti-aging effects were observed, and most interesting to rosacea sufferers were a decrease in redness in over 90% of test subjects by an average of 30% or more.
A product of Silab, Actiflow® is comprised of saccharomyces cerevisiae extract, otherwise known as baker's or brewer's yeast. The main purpose of Actiflow® is to improve blood circulation in the tiny blood vessels just beneath the skin, and to improve vascular congestion. Because blood circulation, vascular congestion, and the degeneration of vascular health are major contributing factors to rosacea, Actiflow® is a useful active ingredient in the treatment of rosacea as well.
Actiflow® has been clinically proven to have anti-inflammatory and anti-redness properties to help address the ultra-sensitive skin conditions of rosacea sufferers, and soothe and calm inflamed, discoloured skin.
It has been especially formulated for sensitive skin and will not aggravate the rosacea condition, but instead works to soothe and calm the factors that cause redness and inflammation.
Produced by Silab, Mediacalm® is particularly useful for rosacea treatment because its active ingredient Boerhavia Difussa Root Extract significantly reduces inflammation, soothes irritated skin, and restores a normal sensitivity threshold to the skin.
Since hyper-sensitivity and inflammation are at the root of rosacea, this ingredient is key in addressing rosacea concerns. Once inflammation is soothed and regulated, rosacea-prone skin not only looks and feels better but is better protected against triggers that cause episodes of rosacea.
Mediacalm® is also known to reduce erythema (redness) in the process of reducing sensitivity, while also reducing the instance of “prickling skin” common to rosacea. It is being hailed as the “neurocosmetic answer for sensitive skin.”
Also known as vitamin U, Allantoin has been used to treat dry and damaged skin since the 16th century. Allantoin is a moisturizer and a kerolytic -- which means it softens the keratin in the skin (the key structural protein in the epidermis), allowing skin to heal more quickly and to absorb moisture more effectively.
Known for its anti-inflammatory, antiseptic, and soothing properties, Allantoin is often used in rosacea and acne treatment.
As well as being a natural anti-irritant, Allantoin is used to stimulate regeneration of healthy skin cell tissues. At the same time, it acts as a chemical “debrider,” which means it helps slough off dead and damaged skin cells and tissues. Together, these actions help speed the general healing of the skin. The red, inflamed, and thickened skin of rosacea is softened, calmed, and healed through topical use of Allantoin.
Skin moisturizer that enhances the bioavailability of other ingredients. Proven in study to increase skin moisturization by 100% in a 14-day period. Read the study.
Permeates skin by moving between cells rather than passing through the cells directly. Clinically proven to protect against UV damage, promote collagen synthesis, reduce deep wrinkles, smooth skin surface, and promote moisture retention.
Other Featured Ingredients:
Camellia Sinensis (Green Tea) Leaf Extract: Helps reduce redness and is a powerful anti-inflammatory that contains antioxidants to fight the environmental free radicals that damage the DNA of skin cells. A polyphenol (antioxidant) in green tea called Epigallocatechin galate (EGCC) is 200 times more powerful than vitamin E for fighting free radicals, and has been shown to be effectively absorbed via the skin.
Green tea helps inhibit the action of collagenase, which is the enzyme that breaks down collagen; using green tea extract topically promotes collagen health and formation, thereby promoting skin firmness and elasticity. Green tea extract is also an astringent, and also contains Methylxanthines, which stimulate skin microcirculation and help provide healthy skin tone. Green tea extract is photo protective (which means it boosts the skin’s natural defenses against UV rays) and reduces erythema (redness of the skin cause by engorged capillaries beneath the skin).
Study: Tanweer Syed, M.D., Ph.D., developed a green tea extract containing 2 percent polyphenone. In 2005, he reported women treated with the cream had a 70-percent improvement in rosacea compared with women treated with a placebo.
Syed tested the green tea extract cream twice a day for four weeks in 60 women aged 25 to 50 with visible signs of rosacea. At the end of four weeks, “marked beneficial improvement” was observed in both groups. However, treatment with the green tea extract resulted in significantly fewer facial inflammatory lesions than the placebo treatment, with clearing, minimal or mild improvement of inflammation seen in 70 percent of those treated with the extract cream.
Vitis Vinifera (Grape) Seed Extract: High in antioxidants, especially bioflavonoids, which have antioxidant properties that are up to 50 times more powerful than vitamin E and 25 times more powerful than vitamin C. Useful for fighting free radicals and for maintaining capillary health, grape seed extract offers powerful protection against the breakdown of collagen, elastin, and hyaluronic acid, which together make up much of the cellular matrix and support the capillaries. When capillaries are strong, they stretch to allow red blood cells through tight spaces, and do not let fluids in the blood leak out. When they are weak, blood can pool and create inflammation. Grape seed extract has also been shown to treat edema (swelling) as well.
Saccharomyces Cerevisiae Extract: A particularly valuable skin-conditioning agent that has been clinically proven more powerful than vitamins A, C, and E in providing skin microrelief results, since it can “act in oxidative stress” -- meaning that it can help correct the cellular imbalance created by damaging free radicals. It also prevents transepidermal water loss, improves skin moisture, and protects skin from free radical damage. It has anti-inflammatory and anti-redness properties and is known to be especially useful for sensitive skin.
Beta Glucan: Sugars extracted from the cell walls of oats and barley, plus bacteria, fungi, yeast, algae and lichens. Beta glucans are applied to the skin for anti-wrinkle purposes, but have a much longer history of use in treating eczema, burns, and wounds, and have been shown to reduce scarring after surgery. Long used as a moisturizer capable of forming a film over the skin, beta glucan is an anti-irritant that stimulates collagen deposition. It also supports the health of macrophages, which are the cells that destroy bacteria, dead or mutated skin cells, environmental toxins, etc. Macrophages exist all over our bodies. Our macrophage cells are damaged over time through exposure to sunlight, soaps and cosmetics, chlorine, and more. When macrophages are brought back to a healthy condition, skin has renewed immunity and can easily remove dead and damaged cells.
Study #1: “In a recent beta glucan skin care study, several hundred women were given a topical cream containing mostly beta glucan. The effects on the signs of aging in the skin were evaluated. Compared with the control group, a 27 percent improvement in skin hydration was observed after eight weeks of use twice daily. An improvement in lines and wrinkles of 47% was measured, firmness and elasticity increased by 60%, and skin color improved by 26%. The rate of skin renewal increased by 34%.”
Study #2: Beta glucan has the ability to penetrate the epidermis and reach the dermis (the middle layer of skin, where wrinkles are formed). As such, it may be used as a transdermal delivery system to deliver other nutrients to the dermis. Beta glucan is currently of interest as a possible non-invasive alternative to Botox. Note that most of the interest in beta glucan is based on the results of one study (2005, Dr. Pillai, International Federation of Societies of Cosmetic Chemists).
Vaccinium Myrtillus (Bilberry) Extract: Contains plant pigments called anthocyanosides that have powerful antioxidant properties as well as vitamin C. Together they scavenge free radicals and help skin maintain elasticity with a healthy collagen and elastin matrix. Often used in the treatment of vascular and vision disorders, bilberry extract is known to improve blood circulation.
Ginkgo Biloba Extract: Works as a vasodilator to increase circulation and improve sebaceous secretions (the skin’s lubricant produced by our tiny sebaceous glands). It helps improve tissue irrigation and activate cell metabolism by increasing glucose and oxygen uptake by the cells. Ginkgo Biloba is an anti-inflammatory, anti-allergenic, and a good antioxidant. It stimulates the fibroblasts to produce collagen and helps strengthen “extracellular fibronectin.”
Caprylic Capric Triglycerides: Forms a barrier on the skin’s surface to protect against moisture loss as well as soothes, softens, and moisturizes skin. It is colorless and odorless and safe for sensitive skin. It goes on smoothly and is rapidly absorbed by the skin and has a light, non-oily texture.
Titanium Dioxide: Titanium Dioxide is used as a physical sun block to help protect sensitive skin against harmful UVA and UVB rays. It is non-irritating and its use is preferred over chemical sunscreens for sensitive skin (which typically reacts to chemical sunscreens -- most sunscreens are chemical rather than physical sun block). Since sun exacerbates rosacea, this ingredient is important for rosacea sufferers, especially since most sun blocks only worsen the condition.
Iron Oxides: Photo-protective, acting as a natural sunscreen to protect skin from damaging UV rays. The pigment of iron oxide is known to be suitable for masking the redness of rosacea.
Silybum Marianum (Milk Thistle) Extract: From the plant Silybum marianum, the active ingredient in the extract is called silymarin, and is made up of three bioflavonoids -- silybin, silydianin, and silychristine -- extracted from the fruit, seeds and leaves of the milk thistle plant. These bioflavonoids have very high antioxidant activity. Milk thistle also smoothes and softens the skin and acts as an anti-inflammatory.
Pinus Pinaster Bark (Maritime Pine) Extract: An excellent source of flavonoids, catechins, proanthocyanidins, and phenoloic acids -- which all act as powerful antioxidants and anti-inflammatories that work to protect the skin from harmful free radicals while strengthening blood vessel walls and capillaries. It has been used topically to heal wounds and other skin conditions for centuries.
Silica: Forms a barrier on the skins surface to help prevent against moisture loss. It provides a smooth feel to the skin and is known to be a non-irritant, particularly useful for acne or rosacea prone skin. Similarly, silica is used in acne treatment to absorb toxins and impurities from the skin.
Panthenol: A derivative of vitamin B5, or pantothenic acid, that is typically plant-derived. Pantothenic acid is a natural substance of all living cells and tissues and is necessary for proper metabolic function and the manufacturing of hormones. Although it is a derivative of vitamin B5, panthenol is considered a pro-vitamin of pantothenic acid and alcohol. Panthenol penetrates into the second layer of skin (the dermis) and can help stabilize the skin's metabolism. Panthenol can aid in evening skin tone by stimulating skin pigment formation. Panthenol penetrates the skin and helps stimulate skin cell renewal and promotes epithelialization, which is the skin's ability to heal over a wound. It is also effective as an anti-inflammatory for skin trauma or allergies.
Sodium Lactate: Acts as a penetration enhancer that alters the skin structure to allow other ingredients to penetrate deeper into the skin. It is used to supplement the skin’s own naturally occurring sodium lactate to provide added moisturization and skin conditioning. Sodium Lactate is a humectant and an exfoliant, and also balances a product’s pH balance. It is one part of the Natural Moisturizing Factor (NMF) and helps renew skin cells. It is also used to prevent pigmentation in the skin and often found in skin whitening products. It has antioxidant properties as well.
The Complete Skinception™ Rosacea Relief Serum Formulation Includes:
ACTIVES: Renovage, Mediacalm, Actiflow EL, Allantoin
DELIVERY: Hydrolite 5, Symglucan
INGREDIENTS: Water, Caprylic Capric Triglycerides, Isopropyl Palmitate, Silica, Titanium Dioxide, Iron Oxides, Pentylene Glycol, Beta Glucan, Teprenone, Butylene Glycol, Boerhavia Difussa Root Extract, Saccharomyces Cerevisiae Extract, Stearyl Alcohol, Panthenol, Magnesium Aluminum Silicate, Glyceryl Stearate, Sodium Stearoyl Lactylate, Allantoin, Sodium Lactate, Camellia Sinensis (Green Tea) Leaf Extract, Vitis Vinifera (Grape) Seed Extract, Vaccinium Myrtillus (Bilberry) Extract, Silybum Marianum (Milk Thistle) Extract, Pinus Pinaster Bark (Maritime Pine) Extract, Ginkgo Biloba Extract, Na-Carbomer, Xanthan Gum, DMDM Hydantoin, Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate.
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